21CHY537 GREEN CHEMISTRY-
Unit-I-
Green Chemistry: Introduction-Definition of green Chemistry, need of green chemistry, basic principles of green chemistry, Green synthesis-Evaluation of the type of the reaction (i) Rearrangements (100% atom economic), (ii) Addition reaction (100% atom economic), Organic reactions by Sonication method: apparatus required examples of sonochemical reactions (Heck, Hundsdiecker and Wittig reactions).
Unit-II-
Selection of solvent: i) Aqueous phase reactions ii) Reactions in ionic liquids, Heckreaction, Suzuki reactions, epoxidation. iii) Solid supported synthesis.
Super critical CO2: Preparation, properties and applications, (decaffeination, dry cleaning).
Unit-III-
Microwave and Ultrasound assisted green synthesis: Apparatus required, examples of MAOS (synthesis of fused anthroquinones, Leukart reductive amination of ketones) – Advantages and disadvantages of MAOS, Aldol condensation-Cannizzaro reaction Diels-Alder reactions-Strecker’s synthesis.
Unit-IV-
Green catalysis: Heterogeneous catalysis, use of zeolites, silica, alumina, supported catalysis-biocatalysis: Enzymes, microbes Phase transfer catalysis (micellar/surfactant).
Unit-V-
Examples of green synthesis / reactions and some real world cases: 1. Green synthesis of the following compounds: adipic acid, catechol, disodium imino di acetate (alternative Strecker’s synthesis), 2. Microwave assisted reaction in water –Hoffmann elimination – methyl benzoate to benzoic acid –oxidation of toluene and alcohols –microwave assisted reactions in organic solvents, Diels-Alder reactions and decarboxylation reaction, 3. Ultrasound assisted reactions–sonochemical Simmons –Smith reaction(ultrasonic alternative to iodine).
TEXTBOOKS:
- Green Chemistry Theory and Practice. P.T.Anatas and J.C. Warner.
- Green Chemistry V.K. Ahluwalia Narosa, New Delhi.
- Real world cases in Green Chemistry M.C. Cann and M.E. Connelly.
- Green Chemistry: Introductory Text M.Lancaster: Royal Society of Chemistry (London).
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