CH-401 4th Semester-

Interhalogen compounds- Basic properties of iodine, pseudo halogens.

Dilute solution- Rault’s law, ideal solution, non- ideal solution, and qualitative treatment of colligative properties relative lowering of vapour pressure, elevation of boiling point, and osmotic pressure-their application in finding molecular weight, Van’t Hoff ‘i’ factor, plasmolysis, haemolysis, isotonic solution, normal saline, role of osmosis in living organism.

Some Reaction of Synthetic Importance- (Mechanism and Importance) Aldol Condensation, Arndt-Eistert Synthesis, Bayer-Villiger Reaction, Bischler-Napieralski Synthesis, Cannizzaro Reaction, Claisen Condensation, Claisen-Schmidt or Claisen Reaction, Dakin Reaction, Dieckmann Reaction, Diel’s-Alder Reaction-Diene Synthesis, Elbs Persulphate Oxidation, Fischer-Indole Synthesis, Fitting-Reaction, Friedal Craft Reaction, Knoevenagel Reaction, Leuckart Reaction, Mannich Reaction, Meerwein-Ponndorf-verley Reduction, Michael Reaction, Oppenaure Oxidation, Peehmann Reaction, Perkin Reaction, Reformatsky Reaction, Reimer-Tiemann Reaction, Sommelet Reaction, Ullmann Reaction, Willgerdot Reaction, Witting Reaction, Wolf-Kishner Reduction.

Some Reagent of Synthetic Importance- Alluminium isopropoxide, Alluminium-t-butoxide, Anhydrous alluminium chloride, Boron trifluoride, N- Bromosuccinimide (NBS), Diazoacetic ester, Diazomethane, Dicyclohexylcarbodiimide (DCC), Girard Reagents, Lead tetraacetate, Liquid ammonia, Lithium alluminium hydride, Osmium tetraoxide, Ozone, Perbenzoic acid, Periodic acid, Platinum and Palladium catalyst, Polyphosphoric acid, Raney nickel, Selenium, Selenium dioxide, Sodamide, Sodium borohydride, Trifluoroacetic acid.

Molecular Rearrangements- Introduction, Rearrangements to electron deficient atoms (C, N, O)( Pinacolpinacolone Rearrangement, Wagner Meerwein Rearrangement, Wolf Rearrangement, Allylic Rearrangement, Sommelet-Hauser Rearrangement, Holfmann Rearrangement, Curtiuss Rearrangement, Schmidt Rearrangement, Lossen Rearrangement, Beckmann Rearrangement, Neber Rearrangement, Baeyer-Villiger Reaction, CumeneHydroperoxide Rearrangement, Dakin Rearrangement); Intermolecular aromatic rearrangement (Orton Rearrangement, Hoofmann-Martius Rearrangement); Intramolecular aromatic rearrangement (Claisen Rearrangement, Benzidine Rearrangement); Mixed types of aromatic rearrangement, Fries Rearrangement.

Organometallic Compounds- Organomagnesium Compounds, Organozinc Compounds, Organolead Compounds, Organocadmium Compounds.

Amino acids, Peptides and Protenins- Amino acids (Preparative Methods, dipolar Nature, Chemical reaction, Detection and Configaration); Peptides (The Peptide Linkage, Peptide Synthesis, Structure of Polypeptides); Proteins (General Characteristics, Classification, Structure).

Carbohydrate- Introduction, occurrence, classification, constitution of glucose, osazone formation, Reaction of glucose and fructose, mutration, cyclic structure- pyranose and furanose form, Epimerisation, Chain lengthening and shortening in aidoses.

Chemicals Kinetics- Rate, order and molecularity of a reaction, rate constants of first and second order reactions, half life period, influence of temperature on reaction rate, activation energy, determination of order of a reaction.

Homogeneous catalysis: Criterion of catalysis, mechanism of catalytic action, enzyme catalysis, industrial catalyst.