CSD -103 Cell Structure & Dynamics-

Origin of life on Earth- The theory of Extraterrestrial contact – import of life through meteorites, Theory of Chemical Evolution, Primitive Earth Conditions – anoxic reductive atmosphere, relatively high temperature, Volcanic eruption, radioactivity, high frequency UV radiation, Abiotic formation of sugars, amino acids, organic acids, purines, pyrimidines, glycerol and formation of nucleotides and their polymerization to RNA on reactive Surfaces, polymerization of amino acids to Polypeptides and Proteins, Ribozymes and RNA World, Formation of DNA, Formation of nucleoproteins, Prions, Natural Selection of Self replicating Polymers.

Basics of Cell Biology (structure & function)- Discovery of cell and Cell Theory; Comparison between plant and animal cells; Cell wall; Plasma membrane; Modification of plasma membrane and intracellular junctions; Cytoskeleton; Protoplasm; Mitochondria; Chloroplast; ER; Golgi complex; Lysosome, endosome and microbodies; Ribosome; Centriole; Nucleus; Chemical components of a cell; Catalysis and use of energy by cells.

Biogenesis of Cellular organelles- Biosynthesis of mitochondria, chloroplast, ER, Golgi complex; Biosynthetic process in ER and golgi apparatus; Protein synthesis and folding in the cytoplasm; Degradation of cellular components.

Structure and function of Prokaryotic cell & its components- The Slime and the cell wall of bacteria containing peptidoglycan and related molecules; the outer membrane of Gram-negative bacteria, the cytoplasmic membrane, Water and ion transport, mesosomes, flagella, Pilus, fimbriae, ribosomes,
carboxysomes, sulfur granules, glycogen, polyphosphate bodies, fat bodies, gas vesicles; endospores, exospores, cysts. Mycelia of fungi and Actinomycetes, Cytoskeleton filament, heterocysts and akinets of Cyanobacteria, Gliding and motility.

Membrane structure & transport- Models of membrane structure, Membrane lipids, proteins and carbohydrates; Solute transport by Simple diffusion, Facilitated diffusion and Active transport.

Cell cycle- An overview of cell cycle; Components of cell cycle control system; Intracellular and Extra-cellular control of cell division, Programmed cell death (Apoptosis), intrinsic & extrinsic pathways of cell death, Apoptosis in relation with Cancer, Viral disease (AIDS) & Organ transplant.