Life Sciences Institute

The Life Sciences Institute (LSI) is a collaborative, multidisciplinary research institution located on the campus of the University of Michigan in Ann Arbor. It encompasses 26 faculty-led teams from 12 schools and departments throughout U-M. The LSI brings together leading scientists from a variety of life science disciplines, working with a range of models systems and cutting-edge research tools, to accelerate breakthroughs and discoveries that will broaden understanding of the basic processes of life and lead to new treatments to improve human health.# ISO CERTIFICATION IN INDIA

Of the university’s $823 million in research expenditures, more than half is allocated for research in the life sciences, and the LSI is a cornerstone of this effort.# ISO CERTIFICATION IN INDIA

History

In 1998, the University of Michigan formed a commission to create a vision for the future of the life sciences at the university. In response to the commission’s recommendations, in 1999, the Regents of the University of Michigan unanimously approved the construction of the Life Sciences Institute, noting that “the creation of a life sciences institute will eliminate the structural barriers to a shared research and learning experience that will be valuable for both basic and applied research.”Initial funding of $100 million was provided for the creation of wet lab space, in addition to the $130 million for the endowment and startup costs.# ISO CERTIFICATION IN INDIA

The first faculty members moved into the building and opened their labs in September 2003, and the institute celebrated its grand opening in May 2004. That same year, the institute’s first two research cores opened, supporting high-throughput screening and structural biology research : the Center for Structural Biology and the Center for Chemical Genomics. The cryo-electron microscopy facility opened in 2009, expanding the institute’s structural biology capabilities. In 2018, with support from the U-M Biosciences Initiative, the institute began expanding the cryo-EM program and also launched its Natural Products Discovery Core.# ISO CERTIFICATION IN INDIA

In 2021, the building that houses the institute was renamed Mary Sue Coleman Hall, in honor of President Emerita Mary Sue Coleman.# ISO CERTIFICATION IN INDIA

Leadership

Roger D. Cone, Ph.D., began his tenure as the Mary Sue Coleman Director of the University of Michigan Life Sciences Institute in September 2016. A leading researcher in brain regulation of body weight, Cone also serves as vice provost and director of U-M’s biosciences initiative. The managing director is Anna Schork.# ISO CERTIFICATION IN INDIA

The institute’s first director was Jack E. Dixon. In 2002, Mary Sue Coleman, U-M’s president, appointed cell biologist and expert on insulin signaling Alan R. Saltiel as director. Saltiel served as the director until 2015, followed by interim director Stephen Weiss, M.D., who led the institute from 2015 to 2016.# ISO CERTIFICATION IN INDIA

Research

The Center for Stem Cell Biology

The Life Sciences Institute is a multidisciplinary basic science research institute, with focal strengths in chemical and structural biology. Its 23 faculty members lead labs specializing in a wide range of life sciences disciplines, including:# ISO CERTIFICATION IN INDIA

• cell biology
• genetics
• cancer biology
• metabolism and obesity
• neuroscience and neurodegeneration
• infectious disease
• structural biology
• chemical biology
• chemistry