21PHY335 BIOPHYSICS-
UNIT I-
Introduction: Laws of Physics and Chemistry, introduction to crystallography, Introduction to chromatography, electrophoresis Physico-Chemical Techniques to study Biomolecules: hydration of macromolecules, diffusion of osmosis, sedimentation, ultracentrifuge, rotational dissuasion, light scattering, small angle X-ray scattering, Mass spectrometry.
UNIT II-
Spectroscopy: UV spectroscopy, circular dichroism, Fluorescence spectroscopy, IR, Raman and Electron spin spectroscopy, NMR spectroscopy.
UNIT III-
Molecular Modeling & Macromolecular Structure: building the structure of H2O2, nucleic-acid structure, monomers, polymers, double helical structure of DNA, Polymorphism and nanostructure of DNA, structure of RNA, protein structure: amino acids, virus structure.
UNIT IV-
Energy Pathways in Biology: free energy, couple reactions, group transfer potential, Pyridine Nucleotide, photosynthesis, energy conversion pathways, membrane transport, Biomechanics: strained muscles, mechanical properties of muscles, cardiovascular system.
UNIT V-
Neurophysics: nervous system, physics of membrane potentials, sensory mechanisms, Origin and evolution of life: prebiotic earth, theories of origin and evolution of life, laboratory experiments on formation of small molecules.
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