BIOL-536 DEVELOPMENTAL BIOLOGY-

UNIT I-

Basic concepts of development: Potency, commitment, specification, induction, competence, determination and differentiation; morphogenetic gradients; cell fate and cell lineages; stem cells; genomic equivalence and the cytoplasmic determinants; imprinting; mutants and transgenics inanalysis of development.

UNIT II-

Gametogenesis: Spermatogenesis, Oogenesis, Oogenesis in insects and mammals.

UNIT III-

Fertilization and early development cell surface molecules in sperm-egg recognition in animals; embryo sac development zygote formation, cleavage, blastula formation, embryonic fields, gastrulation and formation of germ layers in animals.

UNIT IV-

Morphogenesis and organogenesis in animals: Cell aggregation and differentiation, Axes and pattern formation, amphibia and chick; organogenesis –eye lens induction, limb development and regeneration in vertebrates; differentiation of neurons.

UNIT V-

Post embryonic development: larval formation, metamorphosis; environmental regulation of normal development; sex determination.

PRACTICALS:

ï‚· Study of different types of placenta in mammals by charts,
ï‚· Identification of cross sections of chick embryo through eye and ear part, vital staining of chick embryo (in vitro), induced ovulation and fertilization in fishes, Study of fish embryo

Recommended Books:

  1. Gilbert. 2013. Developmental Biology. Sinauer Associates.
  2. Sastry and Shukal. 2007. Developmental Biology. Rastogi publications.
  3. Verma and Agarwal. 2012.Chordate Embryology: Developmental Biology.