MDM-602 Medical Microbiology-
Beneficial Microbial Interactions with Human- Normal microbial population of healthy human body-Skin, mouth, upper respiratory tract, intestinal tract, urino-genital tract, eye.
Harmful Microbial Interactions with Human- Entry of pathogens into the host, types of bacterial pathogens, Mechanism of bacterial pathogenicity, colonization and growth, Virulence, Virulence factors – exotoxins, enterotoxins, endotoxins, neurotoxins, avoidance of host defense mechanisms, damage to host cell, Host factors for infection and innate resistance to infection.
General Account of Epidemiology- Principles of epidemiology, Current epidemics (AIDS,Nosocomical, Acute respiratory Syndrome,) Measures for prevention of epidemics –Global health consideration, Emerging and reemerging infectious diseases Biological warfare and biological weapons.
Person to person Microbial disease- Names of pathogen, disease symptoms, and preventive measures.
- Airborne transmission of diseases by airborne pathogens Streptococcal diseases, Corynebacterium and Diptheria, Bordetella and Whooping cough, Mycobacterium-Leprosy and Tuberculosis, Nisseria meningitides meningitis and meningococcemia, Viruses and respiratory tract infection.
- Direct contact transmission of diseases- Staphylococcus, Helicobactor pylori and Gastric ulcers, Hepatitis viruses
- Sexually transmitted diseases- Gonorrhea and syphilis, AIDS and HIV.
Animal transmitted, Artropod transmitted , Soil borne and Water borne microbial diseases.
Animal transmitted disease- Rabies, Hantavirus pulmonary syndrome.
Artropod transmitted disease- Rickettsia, Malaria, Plague.
Soil borne diseases- Tetanus.
Water borne microbial diseases- Cholera, Typhoid, Amoebiasis, Giardiasis.
Chemical control of Pathogens- Definition and Classification of antibiotics on the basis of structure and mode of action, Assay of antibiotics, antibiotic spectrum Naturally produced drugs, Antibiotics produced by bacteria, actinomycetes and fungi used in chemotherapy, Semisynthetic antibiotic, Sulfa drugs their use and mechanism of action, Naldixic acid, nitrofurans, isonicotinic hydrazide, metronidazole; Prophylactic agents, Drug toxicity, Drug resistance – chromosomal mutation and plasmid-borne multiple drug resistance, cyclic polypeptide antibiotics of bacteria.